Fischer C, Metsger M, Bauch S, Vidal R, Böttcher M, Grote P, Kliem M, and Sauer S. Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells. Science Signaling. 2019 May 14. Vol. 12, Issue 581. DOI: 10.1126/scisignal.aao5820. [Full text]

Kaleviste E, Saare M, Leahy TR, Bondet V, Duffy D, Mogensen TH, Jørgensen SE, Nurm H, Ip W, Davies EG, Sauer S, Syvänen AC, Milani L, Peterson P, Kisand K. Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined. Eur J Immunol. 2019 May;49(5):790-800. doi: 10.1002/eji.201847955. Epub 2019 Mar 7. PMID: 30801692

Haage V, Semtner M, Vidal RO, Hernandez DP, Pong WW, Chen Z, Hambardzumyan D, Magrini V, Ly A, Walker J, Mardis E, Mertins P, Sauer S, Kettenmann H, Gutmann DH. Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma. Acta Neuropathol Commun. 2019 Feb 14;7(1):20. doi: 10.1186/s40478-019-0665-y. PMID: 30764877


Jänes J, Dong Y, Schoof M, Serizay J, Appert A, Cerrato C, Woodbury C, Chen R, Gemma C, Huang N, Kissiov D, Stempor P, Steward A, Zeiser E, Sauer S, Ahringer J. Elife. Chromatin accessibility dynamics across C. elegans development and ageing. 2018 Oct 26;7. pii: e37344. doi: 10.7554/eLife.37344. [Epub ahead of print] PMID: 30362940.

Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, Balint BL, Sweeney HL, Nagy L. The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory. Immunity. 2018 Oct 16;49(4):615-626.e6. doi: 10.1016/j.immuni.2018.09.005. PMID: 30332629.

Czimmerer Z, Nagy ZS, Nagy G, Horvath A, Silye-Cseh T, Kriston A, Jonas D, Sauer S, Steiner L, Daniel B, Deleuze JF, Nagy L. Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages. Mol Cell Endocrinol. 2018 Aug 15;471:63-74. doi: 10.1016/j.mce.2017.07.034. Epub 2017 Jul 31. PMID: 28774779.

Simandi Z, Horvath A, Cuaranta-Monroy I, Sauer S, Deleuze JF, Nagy L. RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification. Mol Cell Endocrinol. 2018 Aug 15;471:51-62. doi: 10.1016/j.mce.2017.07.033. Epub 2017 Aug 2. PMID: 28778663.

Hadizadeh F, Bonfiglio F, Belheouane M, Vallier M, Sauer S, Bang C, Bujanda L, Andreasson A, Agreus L, Engstrand L, Talley NJ, Rafter J, Baines JF, Walter S, Franke A, D'Amato M. Faecal microbiota composition associates with abdominal pain in the general population. Gut. 2018 Apr;67(4):778-779. doi: 10.1136/gutjnl-2017-314792. Epub 2017 Aug 1. PMID: 28765473.

Tolkachov A, Fischer C, Ambrosi TH, Bothe M, Han CT, Muenzner M, Mathia S, Salminen M, Seifert G, Thiele M, Duda GN, Meijsing SH, Sauer S, Schulz TJ, Schupp M. Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone. Mol Cell Biol. 2018 Mar 26. pii: MCB.00599-17. doi: 10.1128/MCB.00599-17. [Epub ahead of print] PMID: 29581184.

Daniel B, Nagy G, Horvath A, Czimmerer Z, Cuaranta-Monroy I, Poliska S, Hays TT, Sauer S, Francois-Deleuze J, Nagy L. The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages. Nucleic Acids Res. 2018 May 18;46(9):4425-4439. doi: 10.1093/nar/gky157. PMID: 29506156.

Pullabhatla V, Roberts AL, Lewis MJ, Mauro D, Morris DL, Odhams CA, Tombleson P, Liljedahl U, Vyse S, Simpson MA, Sauer S, de Rinaldis E, Syvänen AC, Vyse TJ. De novo mutations implicate novel genes in systemic lupus erythematosus. Hum Mol Genet. 2018 Feb 1;27(3):421-429. doi: 10.1093/hmg/ddx407. PMID: 29177435.

Czimmerer Z, Daniel B, Horvath A, Rückerl D, Nagy G, Kiss M, Peloquin M, Budai MM, Cuaranta-Monroy I, Simandi Z, Steiner L, Nagy B Jr, Poliska S, Banko C, Bacso Z, Schulman IG, Sauer S, Deleuze JF, Allen JE, Benko S, Nagy L. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 2018 Jan 16;48(1):75-90.e6. doi: 10.1016/j.immuni.2017.12.010. PMID: 29343442.

Schubert M, Klinger B, Klünemann M, Sieber A, Uhlitz F, Sauer S, Garnett MJ, Blüthgen N, Saez-Rodriguez J. Perturbation-response genes reveal signaling footprints in cancer gene expression. Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6. PMID: 29295995.


Pei W, Feyerabend TB, Rössler J, Wang X, Postrach D, Busch K, Rode I, Klapproth K, Dietlein N, Quedenau C, Chen W, Sauer S, Wolf S, Höfer T, Rodewald HR. Polylox barcoding reveals haematopoietic stem cell fates realized in vivo. Nature. 2017 Aug 24;548(7668):456-460. doi: 10.1038/nature23653. Epub 2017 Aug 16. PMID: 28813413.

Hernáez B, Alonso G, Alonso-Lobo JM, Rastrojo A, Fischer C, Sauer S, Aguado B, Alcamí A. RNA-Seq Based Transcriptome Analysis of the Type I Interferon Host Response upon Vaccinia Virus Infection of Mouse Cells. J Immunol Res. 2017;2017:5157626. doi: 10.1155/2017/5157626. Epub 2017 Feb 9. PMID: 28280747.

Sauer S, Plauth A. Health-beneficial nutraceuticals-myth or reality? Appl Microbiol Biotechnol. 2017 Feb;101(3):951-961. doi: 10.1007/s00253-016-8068-5. Epub 2017 Jan 9. Review. PMID: 28070666.


Plauth A, Geikowski A, Cichon S, Wowro SJ, Liedgens L, Rousseau M, Weidner C, Fuhr L, Kliem M, Jenkins G, Lotito S, Wainwright LJ, Sauer S. Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress. Free Radic Biol Med. 2016 Oct;99:608-622. doi:10.1016/j.freeradbiomed.2016.08.006. PubMed PMID: 27515816.

Nachshon A, Abu-Toamih Atamni HJ, Steuerman Y, Sheikh-Hamed R, Dorman A, Mott R, Dohm JC, Lehrach H, Sultan M, Shamir R, Sauer S, Himmelbauer H, Iraqi FA, Gat-Viks I. Dissecting the Effect of Genetic Variation on the Hepatic Expression of Drug Disposition Genes across the Collaborative Cross Mouse Strains. Front Genet. 2016 Oct 5;7:172. PubMed PMID: 27761138; PubMed Central PMCID: PMC5050206.

Plauth A, Geikowski A, Cichon S, Wowro SJ, Liedgens L, Rousseau M, Weidner C, Fuhr L, Kliem M, Jenkins G, Lotito S, Wainwright LJ, Sauer S. Data of oxygen- and pH-dependent oxidation of resveratrol. Data Brief. 2016 Sep 15;9:433-437. PubMed PMID: 27699197; PubMed Central PMCID: PMC5037118.

Luge T, Fischer C, Sauer S. Efficient Application of De Novo RNA Assemblers for Proteomics Informed by Transcriptomics. J Proteome Res. 2016 Oct 7;15(10):3938-3943. PubMed PMID: 27523192.

Simandi Z, Horvath A, Wright LC, Cuaranta-Monroy I, De Luca I, Karolyi K, Sauer S, Deleuze JF, Gudas LJ, Cowley SM, Nagy L. OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation. Mol Cell. 2016 Aug 18;63(4):647-61. doi: 10.1016/j.molcel.2016.06.039. PubMed PMID: 27499297.

Wallmeier J, Shiratori H, Dougherty GW, Edelbusch C, Hjeij R, Loges NT, Menchen T, Olbrich H, Pennekamp P, Raidt J, Werner C, Minegishi K, Shinohara K, Asai Y, Takaoka K, Lee C, Griese M, Memari Y, Durbin R, Kolb-Kokocinski A, Sauer S, Wallingford JB, Hamada H, Omran H. TTC25 Deficiency Results in Defects of the Outer Dynein Arm Docking Machinery and Primary Ciliary Dyskinesia with Left-Right Body Asymmetry Randomization. Am J Hum Genet. 2016 Aug 4;99(2):460-9. doi:10.1016/j.ajhg.2016.06.014. PubMed PMID: 27486780; PubMed Central PMCID:PMC4974089.

Van Haute L, Dietmann S, Kremer L, Hussain S, Pearce SF, Powell CA, Rorbach J, Lantaff R, Blanco S, Sauer S, Kotzaeridou U, Hoffmann GF, Memari Y, Kolb-Kokocinski A, Durbin R, Mayr JA, Frye M, Prokisch H, Minczuk M. Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3. Nat Commun. 2016 Jun 30;7:12039. doi: 10.1038/ncomms12039. PubMed PMID: 27356879; PubMed Central PMCID: PMC4931328.

Vučićević D, Gehre M, Dhamija S, Friis-Hansen L, Meierhofer D, Sauer S, Ørom UA. The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation. Oncotarget. 2016 Jun 7;7(23):33934-47. doi: 10.18632/oncotarget.8985. PubMed PMID: 27129154; PubMed Central PMCID: PMC5085129.

Weidner C, Rousseau M, Plauth A, Wowro SJ, Fischer C, Abdel-Aziz H, Sauer S. Iberis amara Extract Induces Intracellular Formation of Reactive Oxygen Species and Inhibits Colon Cancer. PLoS One. 2016 Apr 6;11(4):e0152398.

Conrad T, Albrecht AS, de Melo Costa VR, Sauer S, Meierhofer D, Ørom UA. Serial interactome capture of the human cell nucleus. Nat Commun. 2016 Apr 4;7:11212.

Telorac J, Prykhozhij SV, Schöne S, Meierhofer D, Sauer S, Thomas-Chollier M, Meijsing SH. Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements. Nucleic Acids Res. 2016 Mar 25. pii: gkw203. [Epub ahead of print]

Volckmar AL, Han CT, Pütter C, Haas S, Vogel CI, Knoll N, Struve C, Göbel M, Haas K, Herrfurth N, Jarick I, Grallert H, Schürmann A, Al-Hasani H, Hebebrand J, Sauer S, Hinney A. Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing. PLoS One. 2016 Feb 1;11(2):e0147904.

Luge T, Sauer S. Generating Sample-Specific Databases for Mass Spectrometry-Based Proteomic Analysis by Using RNA Sequencing. Methods Mol Biol. 2016;1394:219-32.

Weidner C, Rousseau M, Micikas RJ, Fischer C, Plauth A, Wowro SJ, Siems K, Hetterling G, Kliem M, Schroeder FC, Sauer S. Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. J Nat Prod. 2016 Jan 22;79(1):2-12.

Kremer LS, Distelmaier F, Alhaddad B, Hempel M, Iuso A, Küpper C, Mühlhausen C, Kovacs-Nagy R, Satanovskij R, Graf E, Berutti R, Eckstein G, Durbin R, Sauer S, Hoffmann GF, Strom TM, Santer R, Meitinger T, Klopstock T, Prokisch H, Haack TB. Biallelic Truncating Mutations in TANGO2 Cause Infancy-Onset Recurrent Metabolic Crises with Encephalocardiomyopathy. Am J Hum Genet. 2016 Jan 19. pii: S0002-9297(15)00504-2. doi: 10.1016/j.ajhg.2015.12.009. [Epub ahead of print]

Madrigal I, Alvarez-Mora MI, Rosell J, Rodríguez-Revenga L, Karlberg O, Sauer S, Syvänen AC, Mila M. A novel splicing mutation in the IQSEC2 gene that modulates the phenotype severity in a family with intellectual disability. Eur J Hum Genet. 2016 Jan 6. doi: 10.1038/ejhg.2015.267. [Epub ahead of print]

Lopes F, Barbosa M, Ameur A, Soares G, de Sá J, Dias AI, Oliveira G, Cabral P, Temudo T, Calado E, Cruz IF, Vieira JP, Oliveira R, Esteves S, Sauer S, Jonasson I, Syvänen AC, Gyllensten U, Pinto D, Maciel P. Identification of novel genetic causes of Rett syndrome-like phenotypes. J Med Genet. 2016 Jan 6. pii: jmedgenet-2015-103568. doi: 10.1136/jmedgenet-2015-103568. [Epub ahead of print]


Cui H, Schlesinger J, Schoenhals S, Tönjes M, Dunkel I, Meierhofer D, Cano E, Schulz K, Berger MF, Haack T, Abdelilah-Seyfried S, Bulyk ML, Sauer S, Sperling SR. Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic Acids Res. 2015 Nov 17. pii: gkv1244. [Epub ahead of print]

McGinn S, Bauer D, Brefort T, Dong L, El-Sagheer A, Elsharawy A, Evans G, Falk-Sörqvist E, Forster M, Fredriksson S, Freeman P, Freitag C, Fritzsche J, Gibson S, Gullberg M, Gut M, Heath S, Heath-Brun I, Heron AJ, Hohlbein J, Ke R, Lancaster O, Le Reste L, Maglia G, Marie R, Mauger F, Mertes F, Mignardi M, Moens L, Oostmeijer J, Out R, Pedersen JN, Persson F, Picaud V, Rotem D, Schracke N, Sengenes J, Stähler PF, Stade B, Stoddart D, Teng X, Veal CD, Zahra N, Bayley H, Beier M, Brown T, Dekker C, Ekström B, Flyvbjerg H, Franke A, Guenther S, Kapanidis AN, Kaye J, Kristensen A, Lehrach H, Mangion J, Sauer S, Schyns E, Tost J, van Helvoort JM, van der Zaag PJ, Tegenfeldt JO, Brookes AJ, Mir K, Nilsson M, Willcocks S, Gut IG. New technologies for DNA analysis - a review of the READNA Project. N Biotechnol. 2015 Oct 26. pii: S1871-6784(15)00163-6. doi: 10.1016/j.nbt.2015.10.003. [Epub ahead of print] Review.

Limbach M, Saare M, Tserel L, Kisand K, Eglit T, Sauer S, Axelsson T, Syvänen AC, Metspalu A, Milani L, Peterson P. Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling. J Autoimmun. 2015 Oct 9. pii: S0896-8411(15)30045-7. doi: 10.1016/j.jaut.2015.09.006. [Epub ahead of print]

Sauer S. Ligands for the Nuclear Peroxisome Proliferator-Activated Receptor Gamma. Trends Pharmacol Sci. 2015 Oct;36(10):688-704

Frommer A, Hjeij R, Loges NT, Edelbusch C, Jahnke C, Raidt J, Werner C, Wallmeier J, Große-Onnebrink J, Olbrich H, Cindrić S, Jaspers M, Boon M, Memari Y, Durbin R, Kolb-Kokocinski A, Sauer S, Marthin JK, Nielsen KG, Amirav I, Elias N, Kerem E, Shoseyov D, Haeffner K, Omran H. Immunofluorescence Analysis and Diagnosis of Primary Ciliary Dyskinesia with Radial Spoke Defects. Am J Respir Cell Mol Biol. 2015 Oct;53(4):563-73.

Egerer J, Emmerich D, Fischer-Zirnsak B, Chan WL, Meierhofer D, Tuysuz B, Marschner K, Sauer S, Barr FA, Mundlos S, Kornak U. GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting. J Invest Dermatol. 2015 Oct;135(10):2368-76

Kaiser VB, Svinti V, Prendergast JG, Chau YY, Campbell A, Patarcic I, Barroso I, Joshi PK, Hastie ND, Miljkovic A, Taylor MS; Generation Scotland; UK10K, Enroth S, Memari Y, Kolb-Kokocinski A, Wright AF, Gyllensten U, Durbin R, Rudan I, Campbell H, Polašek O, Johansson Å, Sauer S, Porteous DJ, Fraser RM, Drake C, Vitart V, Hayward C, Semple CA, Wilson JF. Homozygous loss-of-function variants in European cosmopolitan and isolate populations. Hum Mol Genet. 2015 Oct 1;24(19):5464-74

Correia JC, Massart J, de Boer JF, Porsmyr-Palmertz M, Martínez-Redondo V, Agudelo LZ, Sinha I, Meierhofer D, Ribeiro V, Björnholm M, Sauer S, Dahlman-Wright K, Zierath JR, Groen AK, Ruas JL.  Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism. Mol Metab. 2015 Sep 26;4(12):891-902.

Wittig M, Anmarkrud JA, Kässens JC, Koch S, Forster M, Ellinghaus E, Hov JR, Sauer S, Schimmler M, Ziemann M, Görg S, Jacob F, Karlsen TH, Franke A. Development of a high-resolution NGS-based HLA-typing and analysis pipeline. Nucleic Acids Res. 2015 Jun 23;43(11):e70

Haack TB, Jackson CB, Murayama K, Kremer LS, Schaller A, Kotzaeridou U, de Vries MC, Schottmann G, Santra S, Büchner B, Wieland T, Graf E, Freisinger P, Eggimann S, Ohtake A, Okazaki Y, Kohda M, Kishita Y, Tokuzawa Y, Sauer S, Memari Y, Kolb-Kokocinski A, Durbin R, Hasselmann O, Cremer K, Albrecht B, Wieczorek D, Engels H, Hahn D, Zink AM, Alston CL, Taylor RW, Rodenburg RJ, Trollmann R, Sperl W, Strom TM, Hoffmann GF, Mayr JA, Meitinger T, Bolognini R, Schuelke M, Nuoffer JM, Kölker S, Prokisch H, Klopstock T. Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement. Ann Clin Transl Neurol. 2015 May;2(5):492-509.

Fuhr L, Rousseau M, Plauth A, Schroeder FC, Sauer S. Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. J Nat Prod. 2015 May 22;78(5):1160-4.

Llewellyn MS, Messenger LA, Luquetti AO, Garcia L, Torrico F, Tavares SB, Cheaib B, Derome N, Delepine M, Baulard C, Deleuze JF, Sauer S, Miles MA. Deep Sequencing of the Trypanosoma cruzi GP63 Surface Proteases Reveals Diversity and Diversifying Selection among Chronic and Congenital Chagas Disease Patients. PLoS Negl Trop Dis. 2015 Apr 7;9(4):e0003458.

Sauer S, Luge T. Nutriproteomics: Facts, concepts, and perspectives. Proteomics. 2015 Mar;15(5-6):997-1013.

Simandi Z, Czipa E, Horvath A, Koszeghy A, Bordas C, Póliska S, Juhász I, Imre L, Szabó G, Dezso B, Barta E, Sauer S, Karolyi K, Kovacs I, Hutóczki G, Bognár L, Klekner Á, Szucs P, Bálint BL, Nagy L. PRMT1 and PRMT8 Regulate Retinoic Acid-Dependent Neuronal Differentiation with Implications to Neuropathology. Stem Cells. 2015 Mar;33(3):726-41.

Meierhofer D, Weidner C, Sauer S. Correction to "integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs". J Proteome Res. 2015 Mar 6;14(3):1643-4.

Weidner C, Rousseau M, Plauth A, Wowro SJ, Fischer C, Abdel-Aziz H, Sauer S. Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species. Phytomedicine. 2015 Feb 15;22(2):262-270.

Aidhen IS, Mukkamala R, Weidner C, Sauer S. A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors. Org Lett. 2015 Jan 16;17(2):194-7.


Meierhofer D, Weidner C, Sauer S. Integrative analysis of transcriptomics, proteomics, and metabolomics data
of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs. J Proteome Res. 2014 Dec 5;13(12):5592-602. doi: 10.1021/pr5005828.

Madrigal I, Alvarez-Mora MI, Karlberg O, Rodríguez-Revenga L, Elurbe DM, Rabionet R, Mur A, Pie J, Ballesta F, Sauer S, Syvänen AC, Milà M. Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes. J Clin Pathol. 2014 Dec;67(12):1099-103. doi: 10.1136/jclinpath-2014-202537.

Weidner C, Fischer C, Sauer S. PHOXTRACK - a tool for interpreting comprehensive datasets of post-translational modifications of proteins. Bioinformatics. 2014 Dec 1;30(23):3410-1. doi: 10.1093/bioinformatics/btu572.

Almouzni G, Altucci L, Amati B, Ashley N, Baulcombe D, Beaujean N, Bock C, Bongcam-Rudloff E, Bousquet J, Braun S, de Paillerets BB, Bussemakers M, Clarke L, Conesa A, Estivill X, Fazeli A, Grgurevi NA, Gut I, Heijmans BT, Hermouet S, Houwing Duistermaat J, Iacobucci I, Ila J, Kandimalla R, Krauss-Etschmann S, Lasko P, Lehmann S, Lindroth A, Majdi G, Marcotte E, Martinelli G, Martinet N, Meyer E, Miceli C, Mills K, Moreno-Villanueva M, Morvan G, Nickel D, Niesler B, Nowacki M, Nowak J, Ossowski S, Pelizzola M, Pochet R, Poto Nik U, Radwanska M, Raes J, Rattray M, Robinson MD, Roelen B, Sauer S, Schinzer D, Slagboom E, Spector T, Stunnenberg HG, Tiligada E, Torres-Padilla ME, Tsonaka R, Van Soom A, Vidakovi M, Widschwendter M. Relationship between genome and epigenome - challenges and requirements for future research. BMC Genomics. 2014 Jun 18;15(1):487.

Luge T, Kube M, Freiwald A, Meierhofer D, Seemüller E, Sauer S. Transcriptomics assisted proteomic analysis of Nicotiana occidentalis infected by Candidatus Phytoplasma mali strain AT. Proteomics. 2014 Aug;14(16):1882-9. doi: 10.1002/pmic.201300551.

Sauer S. Amorfrutins: A Promising Class of Natural Products that Are Beneficial to Health. Chembiochem. 2014 Jun 16;15(9):1231-8.

Siewert C, Luge T, Duduk B, Seemüller E, Büttner C, Sauer S, Kube M. Analysis of expressed genes of the bacterium 'Candidatus phytoplasma Mali' highlights key features of virulence and metabolism. PLoS One. 2014 Apr 11;9(4):e94391.


Sauer S. Diagnostic proteomics: will this impact the clinic? Proteomics Clin Appl. 2013 Dec;7(11-12):725-6.

Freiwald A, Weidner C, Witzke A, Huang SY, Meierhofer D, Sauer S. Comprehensive proteomic data sets for studying adipocyte-macrophage cell-cell communication. Proteomics. 2013 Oct 31. doi: 10.1002/pmic.201300271. [Epub ahead of print]

Weidner C, Wowro SJ, Freiwald A, Kodelja V, Abdel-Aziz H, Kelber O, Sauer S. Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice. Mol Nutr Food Res. 2013 Nov 24. doi: 10.1002/mnfr.201300477.

Weidner C, Wowro SJ, Rousseau M, Freiwald A, Kodelja V, Abdel-Aziz H, Kelber O, Sauer S. Antidiabetic Effects of Chamomile Flowers Extract in Obese Mice through Transcriptional Stimulation of Nutrient Sensors of the Peroxisome Proliferator-Activated Receptor (PPAR) Family. PLoS One. 2013 Nov 12;8(11):e80335. doi: 10.1371/journal.pone.0080335.

Sauer S. Protein set analyses: how could this impact the clinic? Expert Rev Proteomics. 2013 Aug;10(4):305-7. doi: 10.1586/14789450.2013.814883. No abstract available. Erratum in: Expert Rev Proteomics. 2013 Oct;10(5):503.

Weidner C, Wowro SJ, Freiwald A, Kawamoto K, Witzke A, Kliem M, Siems K, Müller-Kuhrt L, Schroeder FC, Sauer S. Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties. Diabetologia, vol. 56, no. 8, pp. 1802–1812, Aug. 2013.

Sauer S. Mikrobielle Diagnostik mittels Massenspektrometrie. Biospektrum 2013, May, 3, 256-257.

Meierhofer D, Weidner C, Hartmann L, Mayr JA, Han CT, Schroeder FC, Sauer S (2013) Protein sets define disease states and predict in vivo effects of drug treatment. Mol. Cell Proteomics, vol. 12, no. 7, pp. 1965–1979, Jul. 2013.

Holzhauser S, Freiwald A, Weise C, Multhaup G, Han CT, Sauer S (2013) Discovery and Characterization of Protein-Modifying Natural Products by MALDI Mass Spectrometry Reveal Potent SIRT1 and p300 Inhibitors. Angew Chem Int Ed Engl. 2013 May 3;52(19):5171-4.

de Groot JC, Weidner C, Krausze J, Kawamoto K, Schroeder FC, Sauer S, Bussow K (2013) Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor gamma. J. Med. Chem., vol. 56, no. 4, pp. 1535–1543, Feb. 2013.

Feldmann R, Fischer C, Kodelja V, Behrens S, Haas S, Vingron M, Timmermann B, Geikowski A, Sauer S (2013) Genome-wide analysis of LXRalpha activation reveals new transcriptional networks in human atherosclerotic foam cells. Nucleic Acids Res 41:3518-3531

Feldmann R, Geikowski A, Weidner C, Witzke A, Kodelja V, Schwarz T, Gabriel M, Erker T, Sauer S (2013) Foam cell specific LXRalpha ligand. PLoS One 8:e57311

Weimann M, Grossmann A, Woodsmith J, Ozkan Z, Birth P, Meierhofer D, Benlasfer N, Valovka T, Timmermann B, Wanker EE, Sauer S, Stelzl U (2013) A Y2H-seq approach defines the human protein methyltransferase interactome. Nat Methods. 2013 Apr;10(4):339-42.


Kliem M, Sauer S (2012). The essence on mass spectrometry based microbial diagnostics. Curr Opin Microbiol 15:1–6

Weidner C, de Groot JC, Prasad A, Freiwald A, Quedenau C, Kliem M, Witzke A, Kodelja V, Han CT, Giegold S, Baumann M, Klebl B, Siems K, Müller-Kuhrt L, Schürmann A, Schüler R, Pfeiffer AF, Schroeder FC, Büssow K, Sauer S (2012). Amorfrutins are potent antidiabetic dietary natural products. Proc Natl Acad Sci U S A 109(19):7257-62


Freiwald A, Mao L, Kodelja V, Kliem M, Schuldt D, Schreiber S, Franke A, Sauer  S  (2011).  Differential  analysis of Crohn’s disease and ulcerative colitis by mass spectrometry. Inflamm Bowel Dis 17(4):1051-2

Mertes F, Elsharawy A, Sauer S, van Helvoort JM, van der Zaag PJ, Franke A, Nilsson M, Lehrach H, Brookes AJ (2011). Targeted enrichment of genomic DNA regions for next-generation sequencing. Brief Funct Genomics 10(6):374-86


Haseneyer G, Stracke S, Piepho HP, Sauer S, Geiger HH, Graner A (2010). DNA polymorphisms and haplotype patterns of transcription factors involved in barley endosperm development are associated with key agronomic traits. BMC Plant Biol 10:5

Konrad K, Dempfle A, Friedel S, Heiser P, Holtkamp K, Walitza S, Sauer S, Warnke A, Remschmidt H, Gilsbach S, Schäfer H, Hinney A, Hebebrand J, Herpertz-Dahlmann B (2010). Familiality and molecular genetics of attention networks in ADHD. Am J Med Genet B Neuropsychiatr Genet 153B(1):148-58

Sauer S, Kliem M (2010). Mass spectrometry tools for the classification and identification of bacteria. Nature Rev Microbiol 8(1):74-82


Baek YS, Haas S, Hackstein H, Bein G, Hernandez-Santana M, Lehrach H, Sauer S, Seitz H. Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells. BMC Immunol 10:18

Darii E, Lebeau D, Papin N, Rubina  AY,  Stomakhin A,  Tost  J,  Sauer S, Savvateeva E, Dementieva E, Zasedatelev  A,  Makarov  AA,  Gut IG (2009). Quantification of target proteins using hydrogel antibody arrays and MALDI time-of-flight mass spectrometry (A2M2S). N Biotechnol 25(6):404-16

Freiwald A, Sauer S (2009). Phylogenetic classification and identification of bacteria by mass spectrometry. Nat Protoc 4(5):732-42

Stracke S, Haseneyer G, Veyrieras JB, Geiger HH, Sauer S, Graner A, Piepho HP. Association mapping reveals gene action and interactions in the determination of flowering time in barley. Theor Appl Genet 118(2):259-73